Optimization and Validation of an HPLC Method for the Analysis of Carvedilol and Impurities
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DOI: 10.1021/acsomega.5c06016
Abstract: In this study, a liquid chromatography method was developed and validated for the accurate determination of carvedilol content while minimizing interference from impurity C and N-formyl carvedilol and allowing precise impurity analysis. The reliability of… read more here.
Keywords: method; analysis; optimization validation; impurity ... See more keywords
Development and Validation of an HPLC-MS/MS Method for Rapid Simultaneous Determination of Cefprozil Diastereomers in Human Plasma
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DOI: 10.1155/2018/6959761
Abstract: Background Both cis- and trans-cefprozil have antimicrobial activity, but their potencies are quite different. It is therefore necessary to develop a sensitive method to simultaneously determine both isomers for pharmacokinetic and bioequivalence studies. Methods An… read more here.
Keywords: development validation; validation hplc; method; method rapid ... See more keywords
Validation of a HPLC Method for Flavonoid Contents in Spina Gleditsiae and Its Use to Illustrate the Various Quality of Cultivated Varieties
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DOI: 10.1177/1934578x20946258
Abstract: Two cultivated varieties of Gleditsia sinensis Lam, Shuo Spina Gleditsiae (SSG) and Mi Spina Gleditsiae (MSG), are currently used in China as a mixture of the herb Spina Gleditsia. This work evaluates, for the first… read more here.
Keywords: cultivated varieties; quality; flavonoid contents; spina gleditsiae ... See more keywords