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Published in 2019 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.1638
Abstract: Real‐world data and patient‐level data from completed randomized controlled trials are becoming available for secondary analysis on an unprecedented scale. A range of novel methodologies and study designs have been proposed for their analysis or…
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Keywords:
decision;
validation novel;
validation;
novel nonrandomized ... See more keywords
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Published in 2018 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201700362
Abstract: A simple, highly sensitive, and robust CE method applied to the determination of alendronate (ALN) was developed from matrices for tissue engineering, characterized by being highly complex systems. The novel method was based on the…
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Keywords:
validation novel;
development validation;
alendronate;
method ... See more keywords
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Published in 2021 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.453
Abstract: To test a novel, low‐cost, home‐made model for needle aspiration of PTA. To ascertain whether simulation‐based teaching using this model was superior to lecture‐based teaching in increasing confidence and reducing anxiety relating to PTA aspiration.…
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Keywords:
validation novel;
drain gain;
novel quinsy;
gain validation ... See more keywords
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Published in 2021 at "Journal of Gastrointestinal Surgery"
DOI: 10.1007/s11605-020-04872-4
Abstract: Data were collected prospectively from all patients undergoing LA between 2006 and 2019. Demographics and surgical outcomes were analyzed. Complicated appendicitis was defined as a gangrenous or perforated appendix, and severe peritonitis as the presence…
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Keywords:
validation novel;
risk;
development validation;
cohort ... See more keywords
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Published in 2020 at "Journal of Virological Methods"
DOI: 10.1016/j.jviromet.2020.113925
Abstract: Abstract The clinical and epidemiologic management of the SARS-CoV-2 pandemic is critically dependent on molecular assays with short turn-around time. We validated the novel Xpert Xpress SARS-CoV-2 assay using a commercial nucleic acid testing (Roche…
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Keywords:
validation novel;
xpress sars;
novel genexpert;
sars cov ... See more keywords
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Published in 2017 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.6b00980
Abstract: Osteoarthritis (OA) is one of the most prevalent articular diseases. The identification of proteins closely associated with the diagnosis, progression, prognosis, and treatment response is dramatically required for this pathology. In this work, differential serum…
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Keywords:
protein;
validation novel;
biomarkers osteoarticular;
osteoarticular pathologies ... See more keywords
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Published in 2018 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.7b00416
Abstract: Multitargeting or polypharmacological approaches, looking for single chemical entities retaining the ability to bind two or more molecular targets, are a potentially powerful strategy to fight complex, multifactorial pathologies. Unfortunately, the search for multiligand agents…
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Keywords:
validation novel;
identification experimental;
silico identification;
group ... See more keywords
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Published in 2018 at "Journal of Endourology"
DOI: 10.1089/end.2017.0834
Abstract: Abstract Introduction: Nephrolithiasis is one of the most common diseases in urology. According to the EAU Guidelines, a percutaneous nephrolitholapaxy (PNL) is recommended when treating a kidney s...
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Keywords:
validation novel;
effective easy;
cost effective;
percutaneous nephrolitholapaxy ... See more keywords
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Published in 2022 at "Journal of the American Geriatrics Society"
DOI: 10.1111/jgs.18052
Abstract: Measuring multimorbidity in claims data is used for risk adjustment and identifying populations at high risk for adverse events. Multimorbidity indices such as Charlson and Elixhauser scores have important limitations. We sought to create a…
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Keywords:
development validation;
validation novel;
multimorbidity indices;
novel multimorbidity ... See more keywords
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Published in 2021 at "Skin Research and Technology"
DOI: 10.1111/srt.13027
Abstract: Transepidermal water loss (TEWL) and capacitance are used in atopic dermatitis (AD) trials to provide objective data on clinical change and response to therapy. Many barrier devices are costly, limiting their utility. GPSkin is a…
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Keywords:
validation novel;
atopic dermatitis;
patient;
atopic ... See more keywords
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Published in 2017 at "Journal of Intelligent Material Systems and Structures"
DOI: 10.1177/1045389x17689932
Abstract: In the present article, we have investigated the behaviour of magnetorheological fluids under a hydrostatic pressure of up to 40 bar.We have designed, manufactured and tested a magnetorheological damper with a novel architecture, which provides…
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Keywords:
validation novel;
experimental validation;
magnetorheological damper;
internal pressure ... See more keywords