A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor γ Binding Properties and Biological Activities.
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DOI: 10.1021/acs.jmedchem.0c01555
Abstract: A proprietary library of novel N-aryl-substituted amino acid derivatives bearing a hydroxamate head group allowed the identification of compound 3a that possesses weak proadipogenic and peroxisome proliferator-activated receptor γ (PPARγ) activating properties. The systematic optimization… read more here.
Keywords: peroxisome proliferator; properties biological; proliferator activated; substituted valine ... See more keywords