Sacubitril/valsartan attenuates atrial structural remodelling in atrial fibrillation patients
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13937
Abstract: Radiofrequency catheter ablation (RFCA) is now an established therapeutic option for patients with atrial fibrillation (AF), but the long‐term recurrence rate of AF is still high. Sacubitril/valsartan (Sac/Val) is superior to valsartan in attenuating ventricular… read more here.
Keywords: sacubitril valsartan; valsartan attenuates; attenuates atrial; atrial structural ... See more keywords
Valsartan attenuates cardiac dysfunction and remodelling in patients with HCM
Sign Up to like & getrecommendations! Published in 2021 at "Nature Reviews Cardiology"
DOI: 10.1038/s41569-021-00636-y
Abstract: Valsartan is safe and effective in improving cardiac structure and function in patients with early-stage hypertrophic cardiomyopathy, according to results from the phase II VANISH trial. read more here.
Keywords: valsartan attenuates; patients hcm; remodelling patients; cardiac dysfunction ... See more keywords
Valsartan attenuates pulmonary hypertension via suppression of mitogen activated protein kinase signaling and matrix metalloproteinase expression in rodents.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular medicine reports"
DOI: 10.3892/mmr.2017.6706
Abstract: It has previously been demonstrated that the renin-angiotensin system is involved in the pathogenesis and development of pulmonary hypertension (PH). However, the efficacy of angiotensin II type I (AT1) receptor blockers in the treatment of… read more here.
Keywords: pulmonary hypertension; kinase; valsartan attenuates; kinase signaling ... See more keywords