Non‐coaptation of an implanted caval valve leaflets for severe tricuspid regurgitation: Rethinking the concept of “Eustachian ridge?”
Sign Up to like & getrecommendations! Published in 2021 at "Catheterization and Cardiovascular Interventions"
DOI: 10.1002/ccd.29461
Abstract: Severe symptomatic tricuspid regurgitation (TR) remains an undertreated disease. Multiple trans‐catheter treatment options are currently under investigation. Transcatheter caval valve implantation (CAVI) has been utilized as a treatment option and aims at decreasing or eliminating… read more here.
Keywords: tricuspid regurgitation; caval valve; eustachian ridge; valve leaflets ... See more keywords
Well-designed two-fold crosslinked biological valve leaflets with heparin-loaded hydrogel coating for enhancing anticoagulation, endothelialization, and anticalcification.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm00736c
Abstract: Commercial biological valve leaflets (BVLs) crosslinked with glutaraldehyde (GA) are at risk of accelerating damage and even failure, owing to the high cell toxicity of GA, acute thrombosis, and calcification in clinical applications. In this… read more here.
Keywords: biological valve; hydrogel coating; hydrogel; heparin loaded ... See more keywords
Conversion of Flow-restrictive Ahmed Glaucoma Valve to a Nonrestrictive Drainage Implant by Slicing the Valve Leaflets: An In Vitro Study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Glaucoma"
DOI: 10.1097/ijg.0000000000001671
Abstract: Supplemental Digital Content is available in the text. Precis: With a newly designed blade, slicing of the Ahmed glaucoma valve (AGV) leaflets helped to convert the flow-restrictive AGV into a non–flow-restrictive device. Flow characteristics by… read more here.
Keywords: ahmed glaucoma; flow restrictive; agv; flow ... See more keywords
An investigation of the glycosaminoglycan contribution to biaxial mechanical behaviours of porcine atrioventricular heart valve leaflets
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Royal Society Interface"
DOI: 10.1098/rsif.2019.0069
Abstract: The atrioventricular heart valve (AHV) leaflets have a complex microstructure composed of four distinct layers: atrialis, ventricularis, fibrosa and spongiosa. Specifically, the spongiosa layer is primarily proteoglycans and glycosaminoglycans (GAGs). Quantification of the GAGs' mechanical… read more here.
Keywords: atrioventricular heart; valve leaflets; biaxial mechanical; valve ... See more keywords
Ex vivo experimental characterizations for understanding the interrelationship between tissue mechanics and collagen microstructure of porcine mitral valve leaflets.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.2139/ssrn.4142055
Abstract: Unidirectional blood flow in the left side of the heart is regulated by the mitral valve. To better understand the mitral valve function, researchers have examined the structural and mechanical properties of the mitral valve… read more here.
Keywords: mitral valve; valve leaflets; mechanics; tissue mechanics ... See more keywords
Elastogenesis Correlates With Pigment Production in Murine Aortic Valve Leaflets
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2021.678401
Abstract: Objective: Aortic valve (AV) leaflets rely on a precise extracellular matrix (ECM) microarchitecture for appropriate biomechanical performance. The ECM structure is maintained by valvular interstitial cells (VICs), which reside within the leaflets. The presence of… read more here.
Keywords: within leaflets; elastogenesis correlates; valve leaflets; aortic valve ... See more keywords