Hybrid Positron Emission Tomography/Magnetic Resonance Imaging in Arrhythmic Mitral Valve Prolapse.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2020.1555
Abstract: Importance Myocardial replacement fibrosis has been reported to occur in one-third of patients with mitral valve prolapse (MVP) and significant mitral regurgitation (MR). However, it remains unknown whether there are detectable changes in myocardial metabolism… read more here.
Keywords: valve prolapse; fdg uptake; mitral valve; pet mri ... See more keywords
Deleterious variants in DCHS1 are prevalent in sporadic cases of mitral valve prolapse
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.347
Abstract: A recent study identified DCHS1 as a causal gene for mitral valve prolapse. The goal of this study is to investigate the presence and frequency of known and novel variants in this gene in 100… read more here.
Keywords: deleterious variants; valve prolapse; prevalent sporadic; variants dchs1 ... See more keywords
Arrhythmic Mitral Valve Prolapse: JACC Review Topic of the Week.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2018.09.048
Abstract: There is an increasing awareness of the association between mitral valve prolapse and sudden cardiac death. There are several clinical risk factors associated with an increased risk of mitral valve prolapse-related sudden cardiac death, most… read more here.
Keywords: mitral valve; risk; valve prolapse; arrhythmic mitral ... See more keywords
Mitral Valve Prolapse: Multimodality Imaging and Genetic Insights.
Sign Up to like & getrecommendations! Published in 2017 at "Progress in cardiovascular diseases"
DOI: 10.1016/j.pcad.2017.10.007
Abstract: Mitral valve prolapse (MVP) is a common heritable valvulopathy affecting approximately 2.4% of the population. It is the most important cause of primary mitral regurgitation (MR) requiring surgery. MVP is characterized by fibromyxomatous changes and… read more here.
Keywords: valve prolapse; mitral valve; prolapse multimodality; multimodality imaging ... See more keywords
Cardiac computed tomography for the localization of mitral valve prolapse: scallop-by-scallop comparisons with echocardiography and intraoperative findings.
Sign Up to like & getrecommendations! Published in 2019 at "European heart journal cardiovascular Imaging"
DOI: 10.1093/ehjci/jey139
Abstract: AIMS We compared the diagnostic accuracy of cardiac computed tomography (CT) with that of echocardiography for the detection of mitral valve prolapse (MVP) on a scallop-by-scallop basis, using surgical inspection as a reference standard. METHODS… read more here.
Keywords: computed tomography; valve prolapse; prolapse; cardiac computed ... See more keywords
Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapse.
Sign Up to like & getrecommendations! Published in 2022 at "European heart journal"
DOI: 10.1093/eurheartj/ehac049
Abstract: AIMS Mitral valve prolapse (MVP) is a common valvular heart disease with a prevalence of >2% in the general adult population. Despite this high incidence, there is a limited understanding of the molecular mechanism of… read more here.
Keywords: valve prolapse; loci; polygenic risk; mitral valve ... See more keywords
P4172Prevalence and potential genetic determinants of young sudden unexplained death victims with suspected arrhythmogenic mitral valve prolapse
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz745.0743
Abstract: Mitral valve prolapse (MVP) is largely considered a benign condition. Recently, arrhythmogenic MVP, a sudden cardiac death (SCD)-predisposing condition characterized clinically by frequent/complex ventricular arrhythmias likely secondary to prolapsing leaflet-induced fibrosis of the left ventricle… read more here.
Keywords: death; valve prolapse; sudy cases; mitral valve ... See more keywords
P919Ventricular arrhythmias in patients with mitral valve prolapse and severe mitral regurgitation
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz747.0515
Abstract: Mitral valve prolapse (MVP) is known to be associated with ventricular arrhythmias (VA), from symptomatic premature ventricular contractions (PVCs) to malignant ventricular tachycardia (VT) and sudden cardiac death (SCD). Previous studies identified risk factors for… read more here.
Keywords: valve prolapse; mitral regurgitation; prolapse; mitral valve ... See more keywords
Electrical markers and arrhythmic risk associated with myocardial fibrosis in mitral valve prolapse
Sign Up to like & getrecommendations! Published in 2022 at "Europace"
DOI: 10.1093/europace/euac017
Abstract: Abstract Aims We aimed to characterize the substrate of T-wave inversion (TWI) using cardiac magnetic resonance (CMR) and the association between diffuse fibrosis and ventricular arrhythmias (VA) in patients with mitral valve prolapse (MVP). Methods… read more here.
Keywords: valve prolapse; myocardial fibrosis; mitral valve; twi ... See more keywords
Re: Relation between Mitral Valve Prolapse and Erectile Dysfunction (from a Nationwide Case-Control Study).
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Urology"
DOI: 10.1097/ju.0000000000000668
Abstract: available at http://www.ncbi.nlm.nih.gov/pubmed/31514966 Editorial Comment: Previous series have indicated an association between cardiovascular diseases and erectile dysfunction (ED). This case-control study evaluated the association between prior mitral valve prolapse and ED using data from Taiwan’s… read more here.
Keywords: valve prolapse; dysfunction; erectile dysfunction; testosterone ... See more keywords
Mitral valve prolapse and Marfan syndrome
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DOI: 10.1111/chd.12467
Abstract: Marfan syndrome is a multisystemic genetic condition affecting connective tissue. It carries a reduced life expectancy, largely dependent on cardiovascular complications. More common cardiac manifestations such as aortic dissection and aortic valve incompetence have been… read more here.
Keywords: mitral valve; marfan syndrome; valve; valve prolapse ... See more keywords