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Published in 2020 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2020.1555
Abstract: Importance Myocardial replacement fibrosis has been reported to occur in one-third of patients with mitral valve prolapse (MVP) and significant mitral regurgitation (MR). However, it remains unknown whether there are detectable changes in myocardial metabolism…
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Keywords:
valve prolapse;
fdg uptake;
mitral valve;
pet mri ... See more keywords
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Published in 2024 at "Clinical Cardiology"
DOI: 10.1002/clc.24316
Abstract: Malignant ventricular arrhythmia (VA) and sudden cardiac death (SCD) have been reported in patients with mitral valve prolapse (MVP); however, effective risk stratification methods are still lacking. Myocardial fibrosis is thought to play an important…
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Keywords:
ventricular arrhythmia;
mitral valve;
patients mitral;
gadolinium enhancement ... See more keywords
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Published in 2025 at "Journal of Arrhythmia"
DOI: 10.1002/joa3.70108
Abstract: Several autopsy and observational studies have investigated the link between mitral valve prolapse (MVP) and sudden cardiac death (SCD) given the well accepted yet rare occurrence of ventricular arrhythmias (VA). Whether surgical intervention for arrhythmogenic…
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Keywords:
sudden cardiac;
mitral valve;
valve;
cardiac death ... See more keywords
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Published in 2018 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.347
Abstract: A recent study identified DCHS1 as a causal gene for mitral valve prolapse. The goal of this study is to investigate the presence and frequency of known and novel variants in this gene in 100…
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Keywords:
deleterious variants;
valve prolapse;
prevalent sporadic;
variants dchs1 ... See more keywords
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Published in 2024 at "Current Cardiology Reports"
DOI: 10.1007/s11886-024-02030-9
Abstract: To summarize currently available data on the topic of mitral valve prolapse (MVP) and its correlation to the occurrence of atrial and ventricular arrhythmias. To assess the prognostic value of several diagnostic methods such as…
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Keywords:
sudden cardiac;
occurrence;
mitral valve;
population ... See more keywords
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Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2018.09.048
Abstract: There is an increasing awareness of the association between mitral valve prolapse and sudden cardiac death. There are several clinical risk factors associated with an increased risk of mitral valve prolapse-related sudden cardiac death, most…
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Keywords:
mitral valve;
risk;
valve prolapse;
arrhythmic mitral ... See more keywords
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Published in 2017 at "Progress in cardiovascular diseases"
DOI: 10.1016/j.pcad.2017.10.007
Abstract: Mitral valve prolapse (MVP) is a common heritable valvulopathy affecting approximately 2.4% of the population. It is the most important cause of primary mitral regurgitation (MR) requiring surgery. MVP is characterized by fibromyxomatous changes and…
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Keywords:
valve prolapse;
mitral valve;
prolapse multimodality;
multimodality imaging ... See more keywords
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Published in 2025 at "Cardiology in the Young"
DOI: 10.1017/s104795112510125x
Abstract: Abstract Cardio-facial-cutaneous syndrome is a rare genetic disorder that typically presents with a combination of CHDs, distinctive facial features, and cutaneous abnormalities. Cardio-facial-cutaneous syndrome is usually caused by a genetic change in the BRAF gene…
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Keywords:
facial cutaneous;
mitral valve;
cutaneous syndrome;
cardio facial ... See more keywords
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Published in 2025 at "Baylor University Medical Center Proceedings"
DOI: 10.1080/08998280.2025.2464465
Abstract: Abstract We describe a case of likely arrhythmic mitral valve prolapse (MVP) resulting in cardiac arrest, cardiopulmonary resuscitation, and initiation of extracorporeal membranous oxygenation. The case provides the clinical stimulus to review what knowledge exists,…
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Keywords:
arrhythmic mitral;
managing arrhythmic;
mitral valve;
valve prolapse ... See more keywords
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Published in 2019 at "European heart journal cardiovascular Imaging"
DOI: 10.1093/ehjci/jey139
Abstract: AIMS We compared the diagnostic accuracy of cardiac computed tomography (CT) with that of echocardiography for the detection of mitral valve prolapse (MVP) on a scallop-by-scallop basis, using surgical inspection as a reference standard. METHODS…
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Keywords:
computed tomography;
valve prolapse;
prolapse;
cardiac computed ... See more keywords
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Published in 2022 at "European heart journal"
DOI: 10.1093/eurheartj/ehac049
Abstract: AIMS Mitral valve prolapse (MVP) is a common valvular heart disease with a prevalence of >2% in the general adult population. Despite this high incidence, there is a limited understanding of the molecular mechanism of…
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Keywords:
valve prolapse;
loci;
polygenic risk;
mitral valve ... See more keywords