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Celastrol directly binds with VAMP7 and RAB7 to inhibit autophagy and induce apoptosis in preadipocytes

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Published in 2023 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2023.1094584

Abstract: Obesity is one of the most prevalent chronic metabolic diseases, and induction of apoptosis in preadipocytes and adipocytes is a potential strategy to treat obesity. Celastrol represents one of the most robust anti-obesity phytochemicals so… read more here.

Keywords: apoptosis; induce apoptosis; apoptosis preadipocytes; celastrol ... See more keywords