A novel dressing for the combined delivery of platelet lysate and vancomycin hydrochloride to chronic skin ulcers: Hyaluronic acid particles in alginate matrices
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2018.03.024
Abstract: &NA; The aim of the present work was to develop a medication allowing for the combined delivery of platelet lysate (PL) and an anti‐infective model drug, vancomycin hydrochloride (VCM), to chronic skin ulcers. A simple… read more here.
Keywords: combined delivery; delivery platelet; skin; platelet lysate ... See more keywords
Development, evaluation and pharmacokinetic assessment of polymeric microarray patches for transdermal delivery of vancomycin hydrochloride.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.0c00431
Abstract: Methicillin-resistant Staphylococcus aureus (MRSA) can cause harmful and potentially deadly infections. Vancomycin remains the first-line antibiotic treatment for MRSA-derived infections. Nevertheless, as a peptide drug, it is poorly absorbed when administered orally due to its… read more here.
Keywords: transdermal delivery; microarray patches; delivery vancomycin; delivery ... See more keywords
Comparative analysis of pharmacokinetics of vancomycin hydrochloride in rabbits after ocular, intragastric, and intravenous administration by LC-MS/MS
Sign Up to like & getrecommendations! Published in 2020 at "Xenobiotica"
DOI: 10.1080/00498254.2020.1774681
Abstract: Abstract The objective of this study was to compare the pharmacokinetics of vancomycin hydrochloride administered into rabbits through different routes and explore the feasibility of peptide drugs entering the systemic circulation through ocular administration. A… read more here.
Keywords: administration; pharmacokinetics vancomycin; intravenous administration; vancomycin hydrochloride ... See more keywords
In vitro drug release and antibacterial activity evaluation of silk fibroin coated vancomycin hydrochloride loaded poly (lactic-co-glycolic acid) (PLGA) sustained release microspheres
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomaterials Applications"
DOI: 10.1177/08853282211064098
Abstract: Currently, the treatment of osteomyelitis poses a great challenge to clinical orthopedics. The use of biodegradable materials combined with antibiotics provides a completely new option for the treatment of osteomyelitis. In this study, vancomycin hydrochloride… read more here.
Keywords: loaded microspheres; vancomycin hydrochloride; vitro drug; drug release ... See more keywords
In Vitro Nephrotoxicity and Permeation of Vancomycin Hydrochloride Loaded Liposomes
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14061153
Abstract: Drugs can be toxic to the fetus depending on the amount that permeates across the maternal–fetal barrier. One way to limit the amount which penetrates this barrier is to increase the molecular size of the… read more here.
Keywords: cell; hydrochloride loaded; vancomycin hydrochloride; hydrochloride ... See more keywords