A machine learning model that emulates experts' decision making in vancomycin initial dose planning.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of pharmacological sciences"
DOI: 10.1016/j.jphs.2022.02.005
Abstract: Vancomycin is a glycopeptide antibiotic that is a primary treatment for methicillin-resistant Staphylococcus aureus infections. To enhance its clinical effectiveness and prevent nephrotoxicity, therapeutic drug monitoring (TDM) of trough concentrations is recommended. Initial vancomycin dosing… read more here.
Keywords: vancomycin initial; decision making; machine learning; model ... See more keywords
Effect of vancomycin initial dosing on time to systemic inflammatory response syndrome resolution in patients with methicillin-resistant Staphylococcus aureus bacteremia
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Chemotherapy"
DOI: 10.1080/1120009x.2017.1389807
Abstract: Current guidelines suggest using vancomycin-loading doses for complicated infections despite a lack of evidence to support this practice. To address this gap, we performed a single-centre cohort study of 124 patients with sepsis due to… read more here.
Keywords: vancomycin initial; resolution; staphylococcus aureus; resistant staphylococcus ... See more keywords