Low Serum Trough Concentrations and High Vancomycin Minimum Inhibitory Concentration in Methicillin-Sensitive Staphylococcus aureus From Hemodialysis Patients in Brazil
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DOI: 10.1097/ftd.0000000000000581
Abstract: Background: The empiric antimicrobial therapy for bacteremia of long-term hemodialysis (HD) outpatients is currently based on the combination of vancomycin and gentamicin because of the high frequency of isolated Staphylococcus species. The vancomycin trough level… read more here.
Keywords: vancomycin; vancomycin minimum; methicillin sensitive; staphylococcus aureus ... See more keywords
A randomized phase 2B trial of vancomycin versus daptomycin for the treatment of methicillin-resistant Staphylococcus aureus bacteremia due to isolates with high vancomycin minimum inhibitory concentrations – results of a prematurely terminated study
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DOI: 10.1186/s13063-018-2702-8
Abstract: BackgroundStudies have suggested the reduced effectiveness of vancomycin against methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infections with high vancomycin minimum inhibitory concentrations. Alternative agents such as daptomycin may be considered. We conducted a randomized controlled study… read more here.
Keywords: vancomycin; high vancomycin; minimum inhibitory; treatment ... See more keywords