Genetic characterization of a VanG-type vancomycin-resistant Enterococcus faecium clinical isolate
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkx510
Abstract: Objectives To characterize, phenotypically and genotypically, the first Enterococcus faecium clinical isolate harbouring a vanG operon. Methods The antibiotic resistance profile of E. faecium 16-346 was determined and its whole genome sequenced using PacBio technology.… read more here.
Keywords: vancomycin; enterococcus faecium; vang; faecium ... See more keywords
VanG‐ and D‐Ala‐D‐Ser‐dependent peptidoglycan synthesis and vancomycin resistance in Clostridioides difficile
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DOI: 10.1111/mmi.14980
Abstract: A Clostridioides difficile strain deficient in the ddl gene is unable to synthesize the dipeptide D‐Ala‐D‐Ala, an essential component of peptidoglycan and the target of vancomycin. We isolated spontaneous suppressors of a ∆ddl mutation that… read more here.
Keywords: vancomycin; ala; vang; ala ser ... See more keywords