Articles with "vanin" as a keyword



A Visible to NIR Emission Ratiometric Fluorescent Probe for Detection Vanin-1 in Vivo.

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Published in 2020 at "ACS sensors"

DOI: 10.1021/acssensors.0c00880

Abstract: Pantetheinase (Vanin-1) is an ectoenzyme, which involves the metabolic pathway of coenzyme A (CoA), can decompose pantetheine into pantothenic acid (CoA precursor) and aminothiol cysteamine. Previous studies have revealed that Vanin-1 with essential biological functions… read more here.

Keywords: vanin; nir emission; fluorescent probe; detection ... See more keywords

Visualization-Based Discovery of Vanin-1 Inhibitors for Colitis

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Published in 2022 at "Frontiers in Chemistry"

DOI: 10.3389/fchem.2021.809495

Abstract: The main effect of Vanin-1/VNN1 is related to its pantetheinase sulfhydrylase activity, which can hydrolyze pantetheine into pantothenic acid and cysteamine. In recent studies, the enzymatic activity of vanin-1/VNN1 has been found to be essential… read more here.

Keywords: discovery vanin; visualization based; vanin; based discovery ... See more keywords

In Vivo and In Vitro Evaluation of Urinary Biomarkers in Ischemia/Reperfusion-Induced Kidney Injury

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms222111448

Abstract: Oxidative stress plays an important role in the pathophysiology of acute kidney injury (AKI). Previously, we reported that vanin-1, which is involved in oxidative stress, is associated with renal tubular injury. This study was aimed… read more here.

Keywords: vanin; vivo vitro; kidney injury; aki ... See more keywords