The Rhodococcus equi virulence protein VapA disrupts endolysosome function and stimulates lysosome biogenesis
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DOI: 10.1002/mbo3.416
Abstract: Rhodococcus equi (R. equi) is an important pulmonary pathogen in foals that often leads to the death of the horse. The bacterium harbors a virulence plasmid that encodes numerous virulence‐associated proteins (Vaps) including VapA that… read more here.
Keywords: virulence; rhodococcus equi; lysosome biogenesis; function ... See more keywords
Biogeography of the fish pathogen Aeromonas salmonicida inferred by vapA genotyping
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DOI: 10.1093/femsle/fnz074
Abstract: ABSTRACT A recently described typing system based on sequence variation in the virulence array protein (vapA) gene, encoding the A-layer surface protein array, allows unambiguous subtyping of Aeromonas salmonicida. In the present study, we compile… read more here.
Keywords: fish pathogen; pathogen aeromonas; salmonicida inferred; aeromonas salmonicida ... See more keywords
Differential Effects of Rhodococcus equi Virulence-Associated Proteins on Macrophages and Artificial Lipid Membranes
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DOI: 10.1128/spectrum.03417-22
Abstract: Rhodococcus equi is a major cause of life-threatening pneumonia in foals and occasionally in immunocompromised persons. Virulence-associated protein A (VapA) promotes R. equi multiplication in lung macrophages, which are the major host cells during foal… read more here.
Keywords: rhodococcus equi; vapa; multiplication; virulence ... See more keywords