Semi-PBPK Modeling and Simulation to Evaluate the Local and Systemic Pharmacokinetics of OC-01(Varenicline) Nasal Spray
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DOI: 10.3389/fphar.2022.910629
Abstract: This study aimed to build a nasal semi-physiologically based pharmacokinetic (PBPK) model to predict the intranasal pharmacokinetic (PK) of the OC-01(varenicline) nasal spray and accelerate the development of this drug. Based on the physiology of… read more here.
Keywords: varenicline nasal; pbpk modeling; semi pbpk; nasal spray ... See more keywords