Variability in intestinal drug metabolizing enzymes and transporters in Crohn's disease and potential impact on oral drug absorption
Sign Up to like & getrecommendations! Published in 2025 at "British Journal of Clinical Pharmacology"
DOI: 10.1002/bcp.70019
Abstract: The aim of study was to generate quantitative data on the abundance of drug‐metabolizing enzymes and transporters (DMETs) in inflamed and non‐inflamed Crohn's disease (CD) ileum and colon, for incorporation into physiologically based pharmacokinetic (PBPK)… read more here.
Keywords: crohn disease; enzymes transporters; drug; variability intestinal ... See more keywords