Articles with "variability lrrk2" as a keyword



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Understanding the role of genetic variability in LRRK2 in Indian population

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Published in 2019 at "Movement Disorders"

DOI: 10.1002/mds.27558

Abstract: Genetic variability in LRRK2 has been unequivocally established as a major risk factor for familial and sporadic forms of PD in ethnically diverse populations. read more here.

Keywords: understanding role; role genetic; genetic variability; variability lrrk2 ... See more keywords

The Evolution of Genetic Variability at the LRRK2 Locus

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Published in 2024 at "Genes"

DOI: 10.3390/genes15070878

Abstract: Leucine-rich repeat kinase 2 (LRRK2) c.6055G>A (p.G2019S) is a frequent cause of Parkinson’s disease (PD), accounting for >30% of Tunisian Arab-Berber patients. LRRK2 is widely expressed in the immune system and its kinase activity confers… read more here.

Keywords: genetic variability; variability lrrk2; variability; lrrk2 locus ... See more keywords