SOMDE: A scalable method for identifying spatially variable genes with self-organizing map.
Sign Up to like & getrecommendations! Published in 2021 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btab471
Abstract: MOTIVATION Recent developments of spatial transcriptomic sequencing technologies provide powerful tools for understanding cells in the physical context of tissue microenvironments. A fundamental task in spatial gene expression analysis is to identify genes with spatially… read more here.
Keywords: method identifying; spatially variable; variable genes; expression ... See more keywords
Bayesian hidden mark interaction model for detecting spatially variable genes in imaging-based spatially resolved transcriptomics data
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2024.1356709
Abstract: Recent technology breakthroughs in spatially resolved transcriptomics (SRT) have enabled the comprehensive molecular characterization of cells whilst preserving their spatial and gene expression contexts. One of the fundamental questions in analyzing SRT data is the… read more here.
Keywords: spatially resolved; spatially variable; model; resolved transcriptomics ... See more keywords