Monogenic Common Variable Immunodeficiency (Mo‐CVID) Score for Optimizing the Genetic Diagnosis in Pediatric CVID Cohort
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DOI: 10.1002/eji.202451433
Abstract: Common variable immunodeficiency (CVID) represents an “umbrella” diagnosis due to its clinical and immunological heterogeneity. The primary objective of this study was to describe a cohort of CVID pediatric subjects from clinical, immunological, and genetic… read more here.
Keywords: cvid; cvid score; immunodeficiency cvid; common variable ... See more keywords
Gastrointestinal pathology in Good’s syndrome, thinking beyond common variable immunodeficiency: a clinicopathological observation
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DOI: 10.1007/s00428-025-04069-7
Abstract: Good’s syndrome (GS) is a rare immunodeficiency associated with thymoma, characterized by increased susceptibility to bacterial, viral, and fungal infections, along with autoimmune manifestations. Gastrointestinal symptoms are common in GS, yet its clinical and histopathological… read more here.
Keywords: good syndrome; pathology; common variable; gastrointestinal pathology ... See more keywords
Bialellic Mutations in Tetratricopeptide Repeat Domain 7A (TTC7A) Cause Common Variable Immunodeficiency-Like Phenotype with Enteropathy
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-017-0427-1
Abstract: TTC7A deficiency typically causes severe gastrointestinal manifestations such as multiple intestinal atresia or early-onset inflammatory bowel disease. In some cases, this is associated with severe combined immunodeficiency. Partial loss-of-function mutations appear to be associated with… read more here.
Keywords: phenotype; immunodeficiency; variable immunodeficiency; common variable ... See more keywords
Gastric Cancer Screening in Common Variable Immunodeficiency
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DOI: 10.1007/s10875-018-0546-3
Abstract: Individuals with common variable immunodeficiency (CVID) have an increased risk of gastric cancer, and gastrointestinal lymphoma, yet screening for premalignant gastric lesions is rarely offered routinely to these patients. Proposed screening protocols are not widely… read more here.
Keywords: risk gastric; variable immunodeficiency; gastric cancer; common variable ... See more keywords
Altered Plasma Fatty Acids Associate with Gut Microbial Composition in Common Variable Immunodeficiency.
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DOI: 10.1007/s10875-021-01146-9
Abstract: PURPOSE Fatty acid (FA) abnormalities are found in various inflammatory disorders and have been related to disturbed gut microbiota. Patients with common variable immunodeficiency (CVID) have inflammatory complications associated with altered gut microbial composition. We… read more here.
Keywords: variable immunodeficiency; fatty acids; common variable; gut microbial ... See more keywords
Granulomas in Common Variable Immunodeficiency Display Different Histopathological Features Compared to Other Granulomatous Diseases
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DOI: 10.1007/s10875-024-01817-3
Abstract: Granulomatous disease affects up to 20% of patients with Common Variable Immunodeficiency (CVID). Granulomas are comprised of highly activated immune cells, and emerge in response to antigenic triggers. In CVID granulomas however, the underlying pathophysiology… read more here.
Keywords: granulomas; granulomatous diseases; common variable; variable immunodeficiency ... See more keywords
Common Variable Immunodeficiency Disorder: A Decade of Insights from a Cohort of 150 Patients in India and the Use of Machine Learning Algorithms to Predict Severity
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DOI: 10.1007/s10875-025-01897-9
Abstract: Common Variable Immunodeficiency (CVID) is a heterogeneous disorder characterized by impaired antibody production and recurrent infections. In this study we investigated the clinical and immunological features of CVID in Indian patients and develops a machine… read more here.
Keywords: severity; variable immunodeficiency; common variable; machine learning ... See more keywords
CXCL13 as a Biomarker of Complex Common Variable Immunodeficiency
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DOI: 10.1007/s10875-025-01963-2
Abstract: Common Variable Immunodeficiency (CVID) is a group of heterogeneous disorders with common denominators of impaired antibody production and function, and recurrent infections. Currently, prognostic biomarkers for CVID are limited. CXCL13 is a critical regulator of… read more here.
Keywords: common variable; cxcl13; levels cxcl13; variable immunodeficiency ... See more keywords
Comparison of various classifications for patients with common variable immunodeficiency (CVID) using measurement of B-cell subsets.
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DOI: 10.1016/j.aller.2016.07.001
Abstract: BACKGROUND Common variable immunodeficiency (CVID) is a heterogeneous disease, characterised by hypogammaglobulinaemia leading to recurrent infections and various complications. The aim of this study was to classify CVID patients based on four known classifications (Paris,… read more here.
Keywords: variable immunodeficiency; cell subsets; common variable; cvid ... See more keywords
Clinical and immunological features of 44 common variable immunodeficiency patients: The experience of a single center in Turkey.
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DOI: 10.1016/j.aller.2019.12.008
Abstract: INTRODUCTION AND OBJECTIVES Common variable immunodeficiency (CVID) is one of the most prevalent forms of primary immunodeficiency characterized by hypogammaglobinemia. Its heterogeneous clinical features include recurrent respiratory tract infections and other complications such as gastrointestinal,… read more here.
Keywords: immunodeficiency; variable immunodeficiency; diagnosis; clinical immunological ... See more keywords
The olfactory function in patients with common variable immunodeficiency.
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DOI: 10.1016/j.anorl.2018.02.003
Abstract: AIMS To determine the incidence of olfactory dysfunction in common variable immunodeficiency patients. To evaluate the correlation between olfactory dysfunction and chronic rhinosinusitis in this class of patients. MATERIALS AND METHODS Fifty patients, with a… read more here.
Keywords: patients common; olfactory function; variable immunodeficiency; common variable ... See more keywords