Expression and characterization of monomeric variable lymphocyte receptor B specific to the glycoprotein of viral hemorrhagic septicemia virus (VHSV).
Sign Up to like & getrecommendations! Published in 2018 at "Journal of immunological methods"
DOI: 10.1016/j.jim.2018.08.006
Abstract: Monomeric variable lymphocyte receptor B (VLRB) is one of the smallest binding scaffold (20-25 kDa) from jawless vertebrates, hagfish and lamprey. This relatively new class of binding scaffold has various advantages: i) it has a single… read more here.
Keywords: lymphocyte receptor; monomeric variable; expression; variable lymphocyte ... See more keywords
Identification of variable lymphocyte receptors that can target therapeutics to pathologically exposed brain extracellular matrix
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aau4245
Abstract: This study demonstrates targeting of blood-brain barrier disruption to deliver payloads at sites of neurological disease. Diseases that lead to blood-brain barrier (BBB) disruption will pathologically expose normally inaccessible brain extracellular matrix (ECM) to circulating… read more here.
Keywords: brain ecm; extracellular matrix; brain extracellular; variable lymphocyte ... See more keywords
Alternative splicing derived invertebrate variable lymphocyte receptor displays diversity and specificity in immune system of crab Eriocheir sinensis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1105318
Abstract: Variable lymphocyte receptors (VLRs) play vital roles in adaptive immune system of agnathan vertebrate. In the present study, we first discover a novel VLR gene, VLR2, from an invertebrate, the Chinese mitten crab, Eriocheir sinensis.… read more here.
Keywords: eriocheir sinensis; variable lymphocyte; crab eriocheir; alternative splicing ... See more keywords
Characterizing CD38 expression in terminally differentiated B cells using variable lymphocyte receptor B tetramers
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1451232
Abstract: Introduction CD38 is an ectoenzyme receptor found on hematopoietic cells and its expression is used in the flow cytometric analysis of sub-populations of circulating B cells among peripheral blood mononuclear cells (PBMC) to aid in… read more here.
Keywords: terminally differentiated; variable lymphocyte; receptor; cd38 ... See more keywords