Variable mutation expression in human cancers: A 'hide-and-seek' mechanism linked to differential MHC-I presentation dynamics.
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DOI: 10.1158/1535-7163.mct-21-0831
Abstract: Not all genomic mutations are expressed at the transcript/protein level, which may explain variation in cancer development, prognosis, and treatment response/resistance. In this study, our aim was to describe the prevalence of somatic mutation loss… read more here.
Keywords: mhc; mutation expression; variable mutation; expression ... See more keywords