Association of Mitochondrial Biogenesis With Variable Penetrance of Schizophrenia.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2021.0762
Abstract: Importance Discovery of mechanisms that underlie variable penetrance for neuropsychiatric illness in the context of genetic variants that carry elevated risk can advance novel treatment approaches for these disorders. Objective To test the hypothesis that… read more here.
Keywords: variable penetrance; 22q group; mitochondrial biogenesis; schizophrenia ... See more keywords
Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.039
Abstract: Background: Identifying genes that are essential for mouse embryonic development and survival through term is a powerful and unbiased way to discover possible genetic determinants of human developmental disorders. Characterising the changes in mouse embryos… read more here.
Keywords: highly variable; penetrance abnormal; abnormal phenotypes; variable penetrance ... See more keywords