Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life
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DOI: 10.1016/j.isci.2022.103746
Abstract: Summary Monoclonal IgG antibodies are the fastest growing class of biologics, but large differences exist in their plasma half-life in humans. Thus, to design IgG antibodies with favorable pharmacokinetics, it is crucial to identify the… read more here.
Keywords: half life; plasma half; transport; variable sequences ... See more keywords