Detecting de novo mitochondrial mutations in angiosperms with highly divergent evolutionary rates.
Sign Up to like & getrecommendations! Published in 2021 at "Genetics"
DOI: 10.1093/genetics/iyab039
Abstract: Although plant mitochondrial genomes typically show low rates of sequence evolution, levels of divergence in certain angiosperm lineages suggest anomalously high mitochondrial mutation rates. However, de novo mutations have never been directly analyzed in such… read more here.
Keywords: mitochondrial mutation; variant frequencies; mitochondrial mutations; sequence evolution ... See more keywords
Pharmacogenetic allele variant frequencies: An analysis of the VA’s Million Veteran Program (MVP) as a representation of the diversity in US population
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0274339
Abstract: We present allele frequencies of pharmacogenomics relevant variants across multiple ancestry in a sample representative of the US population. We analyzed 658,582 individuals with genotype data and extracted pharmacogenomics relevant single nucleotide variant (SNV) alleles,… read more here.
Keywords: pharmacogenetic allele; variant frequencies; allele; population ... See more keywords