Targeted Degradation of 53BP1 Using Ubiquitin Variant Induced Proximity
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DOI: 10.3390/biom12040479
Abstract: In recent years, researchers have leveraged the ubiquitin-proteasome system (UPS) to induce selective degradation of proteins by E3 ubiquitin ligases, which has great potential as novel therapeutics for human diseases, including cancer and neurodegenerative disorders.… read more here.
Keywords: ubiquitin variant; targeted degradation; proximity; variant induced ... See more keywords