Robotic Construction and Screening of Lanthipeptide Variant Libraries in Escherichia coli.
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DOI: 10.1021/acssynbio.2c00344
Abstract: Lanthipeptides are a major class of ribosomally synthesized and post-translationally modified peptides (RiPPs) characterized by thioether cross-links called lanthionine (Lan) and methyllanthionine (MeLan). Previously, we developed a method to produce mature lanthipeptides in recombinant Escherichia… read more here.
Keywords: escherichia coli; robotic construction; construction screening; variant libraries ... See more keywords