A dominant negative variant of RAB5B disrupts maturation of surfactant protein B and surfactant protein C
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DOI: 10.1073/pnas.2105228119
Abstract: Significance The Rab5 GTPase functions in early endosome (EE) fusion in the endocytic pathway. Here, we propose that RAB5B also has a noncanonical vesicular fusion function in the regulated secretion pathway that produces mature surfactant… read more here.
Keywords: variant rab5b; rab5b; surfactant protein; lung ... See more keywords