Variant-specific SARS-CoV-2 within-host kinetics.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medical virology"
DOI: 10.1002/jmv.27757
Abstract: Since early 2021, SARS-CoV-2 variants of concern (VOCs) have been causing epidemic rebounds in many countries. Their properties are well characterised at the epidemiological level but the potential underlying within-host determinants remain poorly understood. We… read more here.
Keywords: specific sars; within host; cov within; variant specific ... See more keywords
Three J-proteins impact Hsp104-mediated variant-specific prion elimination: a new critical role for a low-complexity domain
Sign Up to like & getrecommendations! Published in 2019 at "Current Genetics"
DOI: 10.1007/s00294-019-01006-5
Abstract: Prions are self-propagating protein isoforms that are typically amyloid. In Saccharomyces cerevisiae , amyloid prion aggregates are fragmented by a trio involving three classes of chaperone proteins: Hsp40s, also known as J-proteins, Hsp70s, and Hsp104.… read more here.
Keywords: prion; low complexity; variant specific; hsp104 mediated ... See more keywords
A normative chart for cognitive development in a genetically selected population
Sign Up to like & getrecommendations! Published in 2021 at "Neuropsychopharmacology"
DOI: 10.1038/s41386-021-00988-6
Abstract: Certain pathogenic genetic variants impact neurodevelopment and cause deviations from typical cognitive trajectories. Understanding variant-specific cognitive trajectories is clinically important for informed monitoring and identifying patients at risk for comorbid conditions. Here, we demonstrate a… read more here.
Keywords: cognitive development; chart cognitive; variant specific; normative chart ... See more keywords
SARS-CoV-2 Variant-Specific mRNA Vaccine: Pros and Cons.
Sign Up to like & getrecommendations! Published in 2023 at "Viral immunology"
DOI: 10.1089/vim.2022.0121
Abstract: Emerging severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants have raised concerns about the efficacy of vaccines. The present study aimed to compare the potential of Delta and Omicron variant-specific mRNA vaccines in inducing immune responses.… read more here.
Keywords: delta; specific mrna; variant specific; mrna vaccine ... See more keywords
Variant-specific changes in RAC3 function disrupt corticogenesis in neurodevelopmental phenotypes
Sign Up to like & getrecommendations! Published in 2022 at "Brain"
DOI: 10.1093/brain/awac106
Abstract: Abstract Variants in RAC3, encoding a small GTPase RAC3 which is critical for the regulation of actin cytoskeleton and intracellular signal transduction, are associated with a rare neurodevelopmental disorder with structural brain anomalies and facial… read more here.
Keywords: brain; variant specific; corticogenesis; rac3 variants ... See more keywords
Design of SARS-CoV-2 Variant-Specific PCR Assays Considering Regional and Temporal Characteristics
Sign Up to like & getrecommendations! Published in 2022 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.02289-21
Abstract: Monitoring the introduction and prevalence of variants of concern (VOCs) and variants of interest (VOIs) in a community can help the local authorities make informed public health decisions. PCR assays can be designed to keep… read more here.
Keywords: variant specific; pcr; pcr assays; sars cov ... See more keywords
Catching the Wave: Detecting Strain-Specific SARS-CoV-2 Peptides in Clinical Samples Collected during Infection Waves from Diverse Geographical Locations
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14102205
Abstract: The Coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) resulted in a major health crisis worldwide with its continuously emerging new strains, resulting in new viral variants that… read more here.
Keywords: variant specific; sars cov; catching wave; infection waves ... See more keywords
PRMT8 demonstrates variant-specific expression in cancer cells and correlates with patient survival in breast, ovarian and gastric cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Oncology letters"
DOI: 10.3892/ol.2017.5671
Abstract: Recent emphasis has been placed on the role of epigenetic regulators and epigenetic marks as biomarkers for cancer diagnosis and prognosis, and as therapeutic targets for treatment. One such class of regulators is the protein… read more here.
Keywords: variant specific; expression; prmt8 expression; cancer ... See more keywords