The roles of RNA processing in translating genotype to phenotype
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Molecular Cell Biology"
DOI: 10.1038/nrm.2016.139
Abstract: A goal of human genetics studies is to determine the mechanisms by which genetic variation produces phenotypic differences that affect human health. Efforts in this respect have previously focused on genetic variants that affect mRNA… read more here.
Keywords: processing translating; variants affect; genotype phenotype; translating genotype ... See more keywords
Studying how genetic variants affect mechanism in biological systems.
Sign Up to like & getrecommendations! Published in 2018 at "Essays in biochemistry"
DOI: 10.1042/ebc20180021
Abstract: Genetic variants are currently a major component of system-wide investigations into biological function or disease. Approaches to select variants (often out of thousands of candidates) that are responsible for a particular phenomenon have many clinical… read more here.
Keywords: variants affect; studying genetic; mechanism; genetic variants ... See more keywords