DNA methylation and histone variants in aging and cancer.
Sign Up to like & getrecommendations! Published in 2021 at "International review of cell and molecular biology"
DOI: 10.1016/bs.ircmb.2021.06.002
Abstract: Aging-related diseases such as cancer can be traced to the accumulation of molecular disorder including increased DNA mutations and epigenetic drift. We provide a comprehensive review of recent results in mice and humans on modifications… read more here.
Keywords: variants aging; histone variants; cancer; methylation histone ... See more keywords
Exonic Variants in Aging-Related Genes Are Predictive of Phenotypic Aging Status
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2019.01277
Abstract: Background: Recent studies investigating longevity have revealed very few convincing genetic associations with increased lifespan. This is, in part, due to the complexity of biological aging, as well as the limited power of genome-wide association… read more here.
Keywords: variants aging; aging status; aging related; related genes ... See more keywords