Non-Coding Variants Connect Enhancer Dysregulation with Nuclear Receptor Signaling in Hematopoietic Malignancies.
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DOI: 10.1158/2159-8290.cd-19-1128
Abstract: Mutations in protein-coding genes are well established as the basis for human cancer, yet it remains elusive how alterations within non-coding genome, a substantial fraction of which contain cis-regulatory elements (CREs), contribute to cancer pathophysiology.… read more here.
Keywords: variants connect; coding variants; hematopoietic malignancies; non coding ... See more keywords