Molecular variants of SARS-CoV-2: antigenic properties and current vaccine efficacy
Sign Up to like & getrecommendations! Published in 2022 at "Medical Microbiology and Immunology"
DOI: 10.1007/s00430-022-00729-6
Abstract: An ongoing pandemic of newly emerged SARS-CoV-2 has puzzled many scientists and health care policymakers around the globe. The appearance of the virus was accompanied by several distinct antigenic changes, specifically spike protein which is… read more here.
Keywords: variants sars; molecular variants; sars cov; virus ... See more keywords
Waves and variants of SARS-CoV-2: understanding the causes and effect of the COVID-19 catastrophe
Sign Up to like & getrecommendations! Published in 2021 at "Infection"
DOI: 10.1007/s15010-021-01734-2
Abstract: The coronavirus disease-19 has left a permanent mark on the history of the human race. Severe acute respiratory syndrome coronavirus-2 is a positive-sense single-stranded RNA virus, first reported in Wuhan, China, in December 2019 and… read more here.
Keywords: understanding causes; catastrophe; variants sars; sars cov ... See more keywords
Implications derived from S-protein variants of SARS-CoV-2 from six continents
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Biological Macromolecules"
DOI: 10.1016/j.ijbiomac.2021.09.080
Abstract: Spike (S) protein is a critical determinant of the infectivity and antigenicity of SARS-CoV-2. Several mutations in the spike protein of SARS-CoV-2 have already been detected, and their effect in immune system evasion and enhanced… read more here.
Keywords: protein variants; derived protein; implications derived; sars cov ... See more keywords
A low-cost TaqMan minor groove binder probe-based one-step RT-qPCR assay for rapid identification of N501Y variants of SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Virological Methods"
DOI: 10.1016/j.jviromet.2021.114333
Abstract: The increasing prevalence of N501Y variants of SARS-CoV-2 has kindled global concern due to their enhanced transmissibility. Genome sequencing is the gold standard method to identify the emerging variants of concern. But it is time-consuming… read more here.
Keywords: n501y variants; qpcr assay; sars cov; taqman minor ... See more keywords
501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to bamlanivimab in vitro
Sign Up to like & getrecommendations! Published in 2021 at "mAbs"
DOI: 10.1080/19420862.2021.1919285
Abstract: ABSTRACT The newly emerging variants of SARS-CoV-2 from South Africa (B.1.351/501Y.V2) and Brazil (P.1/501Y.V3) have led to a higher infection rate and reinfection of COVID-19 patients. We found that the mutations K417N, E484K, and N501Y… read more here.
Keywords: binding bamlanivimab; binding; rbd; sars cov ... See more keywords
Immune responses against different variants of SARS-CoV-2 including omicron following six months of administration of heterologous prime-boost COVID-19 vaccine
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Travel Medicine"
DOI: 10.1093/jtm/taac033
Abstract: Comparative analysis at one- and six-months post-vaccination showed modest reduction in S1-RBD IgG antibody and NAb titers against B.1, Alpha, Beta and Delta variants in heterologous and homologous vaccine recipients groups. However, significant reduction in… read more here.
Keywords: different variants; immune responses; six months; responses different ... See more keywords
A Next-Generation Vaccine Candidate Using Alternative Epitopes to Protect against Wuhan and All Significant Mutant Variants of SARS-CoV-2: An Immunoinformatics Approach
Sign Up to like & getrecommendations! Published in 2021 at "Aging and Disease"
DOI: 10.14336/ad.2021.0518
Abstract: Newly emerging significant SARS-CoV-2 variants such as B.1.1.7, B.1.351, and B.1.1.28 are the variant of concern (VOC) for the human race. These variants are getting challenging to contain from spreading worldwide. Because of these variants,… read more here.
Keywords: vaccine; next generation; variants sars; sars cov ... See more keywords
Omicron variants of SARS-CoV-2 and long COVID
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1061686
Abstract: Understanding the epidemiology of long COVID and emerging variants has significant public-health implications as physical interventions and restrictions that help limit viral spread are eased globally. Here, we provide rationales for the necessity of updating… read more here.
Keywords: long covid; cov long; omicron variants; variants sars ... See more keywords
Variants of SARS-CoV-2: Influences on the Vaccines’ Effectiveness and Possible Strategies to Overcome Their Consequences
Sign Up to like & getrecommendations! Published in 2023 at "Medicina"
DOI: 10.3390/medicina59030507
Abstract: The immune response elicited by the current COVID-19 vaccinations declines with time, especially among the immunocompromised population. Furthermore, the emergence of novel SARS-CoV-2 variants, particularly the Omicron variant, has raised serious concerns about the efficacy… read more here.
Keywords: vaccines effectiveness; influences vaccines; variants sars; consequences variants ... See more keywords
Transmission Dynamics and Genomic Epidemiology of Emerging Variants of SARS-CoV-2 in Bangladesh
Sign Up to like & getrecommendations! Published in 2022 at "Tropical Medicine and Infectious Disease"
DOI: 10.3390/tropicalmed7080197
Abstract: With the progression of the global SARS-CoV-2 pandemic, the new variants have become more infectious and continue spreading at a higher rate than pre-existing ones. Thus, we conducted a study to explore the epidemiology of… read more here.
Keywords: december 2020; emerging variants; epidemiology emerging; variants sars ... See more keywords
The Spike of Concern—The Novel Variants of SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2021 at "Viruses"
DOI: 10.3390/v13061002
Abstract: The high sequence identity of the first SARS-CoV-2 samples collected in December 2019 at Wuhan did not foretell the emergence of novel variants in the United Kingdom, North and South America, India, or South Africa… read more here.
Keywords: spike concern; concern novel; novel variants; sars cov ... See more keywords