Structural Variation in Cancer: Role, Prevalence, and Mechanisms.
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DOI: 10.1146/annurev-genom-120121-101149
Abstract: Somatic rearrangements resulting in genomic structural variation drive malignant phenotypes by altering the expression or function of cancer genes. Pan-cancer studies have revealed that structural variants (SVs) are the predominant class of driver mutation in… read more here.
Keywords: variation cancer; cancer role; structural variation; cancer ... See more keywords