Using single nucleotide variations in single-cell RNA-seq to identify subpopulations and genotype-phenotype linkage
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DOI: 10.1038/s41467-018-07170-5
Abstract: Despite its popularity, characterization of subpopulations with transcript abundance is subject to a significant amount of noise. We propose to use effective and expressed nucleotide variations (eeSNVs) from scRNA-seq as alternative features for tumor subpopulation… read more here.
Keywords: single cell; nucleotide variations; variations single; cell ... See more keywords