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Published in 2017 at "Hepatology"
DOI: 10.1002/hep.28979
Abstract: We read with interest the article by Ribeiro de Souza et al. addressing the impact of nonselective beta-blockers (NSBBs) on short-term prognosis in patients with cirrhosis admitted for their first episode of acute variceal bleeding… read more here.
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Published in 2018 at "Hepatology"
DOI: 10.1002/hep.29680
Abstract: Peptic ulcer bleeding (PUB) is among the most common causes of hospitalization worldwide, however, advances in endoscopic and pharmacological therapies have reduced the case fatality rate to 2.1% (1). In contrast, 6-week mortality of acute… read more here.
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Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30220
Abstract: We performed a systematic review with network meta‐analysis (NMA) to compare the efficacy of different approaches in primary prevention of esophageal variceal bleeding and overall survival in patients with cirrhosis with large varices. Thirty‐two randomized… read more here.
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Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30463
Abstract: Current guidelines recommend cirrhotic patients undergo endoscopic screening for varices, unless patients have liver stiffness 150x109 /L1 . Screening for varices presumes we can offer an intervention to reduce risk of first variceal hemorrhage and,… read more here.
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Published in 2020 at "Hepatology"
DOI: 10.1002/hep.31125
Abstract: A hepatic venous pressure gradient (HVPG) decrease of 20% or more (or ≤12 mm Hg) indicates a good prognosis during propranolol/nadolol treatment but requires two HVPG measurements. We aimed to simplify the risk stratification after… read more here.
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Published in 2020 at "Hepatology"
DOI: 10.1002/hep.31477
Abstract: Variceal bleeding is a major complication of portal hypertension in patients with liver cirrhosis. Hemorrhage occurs mainly in the gastrointestinal tract, while extraluminal bleeding is very rare . The role of extraluminal varices in the… read more here.
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Published in 2020 at "Hepatology"
DOI: 10.1002/hep.31519
Abstract: Variceal bleeding is the most severe complication of portal hypertension in patients with cirrhosis. Management of refractory variceal bleeding is a challenging but commonplace scenario, in which usual endoscopic therapies including variceal ligation and/or sclerotherapy… read more here.
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Published in 2022 at "United European Gastroenterology Journal"
DOI: 10.1002/ueg2.12300
Abstract: Abstract Background Transjugular intrahepatic portosystemic shunt (TIPS) may be used as a salvage treatment in patients with cirrhosis and refractory variceal bleeding. Aim To synthesize the available evidence on the efficacy of TIPS in patients… read more here.
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Published in 2021 at "Inflammation"
DOI: 10.1007/s10753-021-01565-1
Abstract: Variceal bleeding is a serious complication in cirrhotic patients and is related to increased expression of inflammatory mediators that accentuate circulatory dysfunction. The study aims to evaluate the performance of high mobility protein group 1… read more here.
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Published in 2021 at "Drugs"
DOI: 10.1007/s40265-021-01493-2
Abstract: Cirrhosis is the fifth leading cause of death in adults. Advanced cirrhosis can cause significant portal hypertension (PH), which is responsible for many of the complications observed in patients with cirrhosis, such as varices. If… read more here.
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Published in 2019 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2019.08.019
Abstract: BACKGROUND & AIMS Transarterial chemoembolization (TACE) is the standard of care for intermediate stage hepatocellular carcinoma (HCC) patients. Variceal bleeding is a life-threatening complication and may alter the initial treatment plan. This study was aimed… read more here.