Using Disease Epidemiology to Optimize Immunization Schedules.
Sign Up to like & getrecommendations! Published in 2017 at "JAMA pediatrics"
DOI: 10.1001/jamapediatrics.2017.2375
Abstract: Macartney et al1 report in this issue of JAMA Pediatrics on the safety of using combination measles-mumps-rubellavaricella (MMRV) vaccine as the second dose of measlesmumps-rubella (MMR) vaccine and sole dose of varicella vaccine in Australia,… read more here.
Keywords: varicella vaccine; mmrv vaccine; age; epidemiology ... See more keywords
Immunogenicity and safety of a live attenuated varicella vaccine in children 1-12 years of age: A randomized, blinded, controlled, non-inferiority phase 3 clinical trial.
Sign Up to like & getrecommendations! Published in 2021 at "Contemporary clinical trials"
DOI: 10.1016/j.cct.2021.106489
Abstract: OBJECTIVES To evaluate the immunogenicity and safety of a live attenuated varicella vaccine produced using a cell factory process. METHODS In this randomized, blinded, controlled, non-inferiority phase 3 clinical trial conducted in Guizhou, healthy children… read more here.
Keywords: varicella vaccine; attenuated varicella; immunogenicity; non inferiority ... See more keywords
Assessment of pre-specified adverse events following varicella vaccine: A population-based self-controlled risk interval study.
Sign Up to like & getrecommendations! Published in 2020 at "Vaccine"
DOI: 10.1016/j.vaccine.2020.01.090
Abstract: BACKGROUND Clinical trials and spontaneous reporting systems have revealed rare but biologically plausible adverse events following varicella immunization. Few post-marketing controlled studies have been conducted to assess the relationship between the varicella vaccine and these… read more here.
Keywords: following varicella; varicella vaccine; risk; varicella ... See more keywords
A Variant Allele in Varicella-Zoster Virus Glycoprotein B Selected during Production of the Varicella Vaccine Contributes to Its Attenuation
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.01864-22
Abstract: The live-attenuated varicella vaccine has reduced the burden of chickenpox. Despite its development in 1974, the molecular basis for its attenuation is still not well understood. ABSTRACT Attenuation of the live varicella Oka vaccine (vOka)… read more here.
Keywords: contributes attenuation; attenuation; varicella vaccine; variant allele ... See more keywords
Varicella Vaccine: a Molecular Variant That May Contribute to Attenuation
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.03120-22
Abstract: Varicella was troublesome when varicella vaccine (vOka) was licensed in the United States. Varicella’s yearly death toll was ~100, indirect costs were massive, and varicella threatened immunocompromised children. ABSTRACT Varicella was troublesome when varicella vaccine… read more here.
Keywords: voka; attenuation; may contribute; varicella vaccine ... See more keywords
Two-dose varicella vaccine effectiveness in China: a meta-analysis and evidence quality assessment
Sign Up to like & getrecommendations! Published in 2021 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-021-06217-1
Abstract: Background The objectives of this review were to evaluate the vaccine effectiveness (VE) of the two-dose varicella vaccine for healthy children in China and explore the application of the approach of Grades of Recommendation, Assessment,… read more here.
Keywords: two dose; quality; varicella vaccine; dose varicella ... See more keywords
Varicella in the Neonatal ICU due to the Varicella Vaccine Oka Strain.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neonatal-perinatal medicine"
DOI: 10.3233/npm-221031
Abstract: BACKGROUND Varicella vaccination of non-immune post-partum women is recommended to reduce the risk of chickenpox in mothers and their infants. Though rare, transmission of the varicella vaccine strain vOka can occur from recent vaccinees to… read more here.
Keywords: neonatal icu; strain; varicella vaccine; vaccine ... See more keywords
Long-term vaccine efficacy of a 2-dose varicella vaccine in China from 2011 to 2021: A retrospective observational study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Public Health"
DOI: 10.3389/fpubh.2022.1039537
Abstract: Objective A 2-dose varicella vaccine immunization strategy has been implemented in many cities in China, but there is few evidence on a long-term evaluation of the efficacy of the 2-dose varicella vaccine from China. This… read more here.
Keywords: long term; vaccine; varicella vaccine; dose varicella ... See more keywords
Twelve Children with Varicella Vaccine Meningitis: Neuropathogenesis of Reactivated Live Attenuated Varicella Vaccine Virus
Sign Up to like & getrecommendations! Published in 2020 at "Viruses"
DOI: 10.3390/v12101078
Abstract: Varicella vaccine is a live attenuated varicella-zoster virus (VZV). Like its parental strain called VZV pOka, the vaccine virus vOka retains some neurotropic properties. To better understand vOka neuropathogenesis, we reassessed 12 published cases of… read more here.
Keywords: meningitis; varicella vaccine; live attenuated; vaccine ... See more keywords
Rational Design of a Skin- and Neuro-Attenuated Live Varicella Vaccine: A Review and Future Perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14050848
Abstract: Primary varicella-zoster virus (VZV) infection causes varicella, which remains a prominent public health concern in children. Current varicella vaccines adopt the live-attenuated Oka strain, vOka, which retains the ability to infect neurons, establish latency and… read more here.
Keywords: skin neuro; neuro attenuated; varicella vaccine; vaccine ... See more keywords
Meningitis without Rash after Reactivation of Varicella Vaccine Strain in a 12-Year-Old Immunocompetent Boy
Sign Up to like & getrecommendations! Published in 2023 at "Vaccines"
DOI: 10.3390/vaccines11020309
Abstract: Acute neurologic complications from Varicella-Zoster-Virus reactivation occur in both immunocompromised and immunocompetent patients. In this report, we describe a case of a previously healthy immunocompetent boy who had received two doses of varicella vaccine at… read more here.
Keywords: immunocompetent boy; meningitis; varicella vaccine; meningitis without ... See more keywords