Analysis of variola virus molecular evolution suggests an old origin of the virus consistent with historical records
Sign Up to like & getrecommendations! Published in 2023 at "Microbial Genomics"
DOI: 10.1099/mgen.0.000932
Abstract: Archaeovirology efforts provided a rich portrait of the evolutionary history of variola virus (VARV, the cause of smallpox), which was characterized by lineage extinctions and a relatively recent origin of the virus as a human… read more here.
Keywords: variola virus; virus; origin virus; historical records ... See more keywords
Identification of Small Molecules with Improved Potency against Orthopoxviruses from Vaccinia to Smallpox
Sign Up to like & getrecommendations! Published in 2022 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00841-22
Abstract: The genus Orthopoxvirus contains several human pathogens, including vaccinia, monkeypox, cowpox, and variola virus, the causative agent of smallpox. Although there are a few effective vaccines, widespread prophylactic vaccination has ceased and is unlikely to… read more here.
Keywords: molecules improved; potency; variola virus; identification small ... See more keywords