Triumphs and tribulations of COVID-19 vaccines: Lessons to be learned from smallpox epidemics in the 1700s
Sign Up to like & getrecommendations! Published in 2021 at "Virchows Archiv"
DOI: 10.1007/s00428-021-03020-w
Abstract: The recent years have been threatened by emerging and reemerging pathogens, like influenza viruses, Ebola virus, Zika virus, and, currently, SARS-CoV-2, which have rapidly spread globally causing large epidemics with devastating health and economic consequences.… read more here.
Keywords: covid vaccines; variolation; clinical trials; vaccine ... See more keywords
Face masking and COVID-19: potential effects of variolation on transmission dynamics
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Royal Society Interface"
DOI: 10.1098/rsif.2021.0781
Abstract: Face masks do not completely prevent transmission of respiratory infections, but masked individuals are likely to inhale fewer infectious particles. If smaller infectious doses tend to yield milder infections, yet ultimately induce similar levels of… read more here.
Keywords: face masking; masking covid; transmission; potential effects ... See more keywords
Edward Jenner’s 1798 report of challenge experiments demonstrating the protective effects of cowpox against smallpox
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Royal Society of Medicine"
DOI: 10.1177/0141076818783658
Abstract: Variolation, that is, the inoculation of smallpox material in people who have not experienced natural smallpox, appears to have been a prophylactic used for centuries in much of Asia and North Africa. It was introduced… read more here.
Keywords: 1798 report; jenner 1798; smallpox; variolation ... See more keywords