Abstract 5006: Discovery of novel heterobifunctional degraders of mutant EGFR proteins for NSCLCs harboring various EGFR mutations
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DOI: 10.1158/1538-7445.am2023-5006
Abstract: Abnormal expression and activation of Epidermal Growth Factor Receptor (EGFR) contribute to malignancy development, especially in non-small cell lung cancers (NSCLCs). Although the first- to third-generation EGFR small molecule inhibitors have made significant progress in… read more here.
Keywords: discovery novel; heterobifunctional degraders; egfr mutations; egfr ... See more keywords