Characterization of background noise in MiSeq MPS data when sequencing human mitochondrial DNA from various sample sources and library preparation methods.
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DOI: 10.1016/j.mito.2020.02.005
Abstract: Improved resolution of massively parallel sequencing (MPS) allows for the characterization of mitochondrial (mt) DNA heteroplasmy to levels previously unattainable with traditional sequencing approaches. An essential criterion for the reporting of heteroplasmy is the ability… read more here.
Keywords: dna; error; background noise; mitochondrial dna ... See more keywords