Articles with "various syngeneic" as a keyword



Abstract 5557: EnanDIM, a family of potent enantiomeric TLR9 agonists, modulate the tumor microenvironment and show single-agent antitumor effects in various syngeneic murine models

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Published in 2018 at "Cancer Research"

DOI: 10.1158/1538-7445.am2018-5557

Abstract: Introduction: TLR9 agonists, being recognized via non-methylated CG-motifs, target the Toll-like receptor 9 (TLR9). This way, they activate the innate and the adaptive immune system. Two different families of TLR9 agonists are currently used in… read more here.

Keywords: tlr9 agonists; various syngeneic; modulate tumor; syngeneic murine ... See more keywords