VARSCOT: variant-aware detection and scoring enables sensitive and personalized off-target detection for CRISPR-Cas9
Sign Up to like & getrecommendations! Published in 2019 at "BMC Biotechnology"
DOI: 10.1186/s12896-019-0535-5
Abstract: BackgroundNatural variations in a genome can drastically alter the CRISPR-Cas9 off-target landscape by creating or removing sites. Despite the resulting potential side-effects from such unaccounted for sites, current off-target detection pipelines are not equipped to… read more here.
Keywords: detection; crispr cas9; variant aware; varscot ... See more keywords