Articles with "vasa recta" as a keyword



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Lgr5-positive endothelial progenitor cells occupy a tumor and injury prone niche in the kidney vasa recta.

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Published in 2020 at "Stem cell research"

DOI: 10.1016/j.scr.2020.101849

Abstract: The Wnt pathway co-receptor, Leucine Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5), labels tumor-prone stem cell populations in certain types of tissue. In this study, we show that ARID1A and PIK3CA mutations in LGR5+… read more here.

Keywords: vasa recta; endothelial progenitor; progenitor cells; kidney ... See more keywords
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Ascending Vasa Recta Are Angiopoietin/Tie2-Dependent Lymphatic-Like Vessels.

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Published in 2018 at "Journal of the American Society of Nephrology : JASN"

DOI: 10.1681/asn.2017090962

Abstract: Urinary concentrating ability is central to mammalian water balance and depends on a medullary osmotic gradient generated by a countercurrent multiplication mechanism. Medullary hyperosmolarity is protected from washout by countercurrent exchange and efficient removal of… read more here.

Keywords: angiopoietin tie2; fluid; ascending vasa; angiopoietin ... See more keywords
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Short-term hypoxia and vasa recta function in kidney slices.

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Published in 2017 at "Clinical hemorheology and microcirculation"

DOI: 10.3233/ch-179230

Abstract: BACKGROUND Descending vasa recta (DVR) supply the inner part of outer renal medulla an area at risk for hypoxic damages. OBJECTIVE We hypothesize increased vasoreactivity after hypoxia/re-oxygenation (H/R) in DVR, which might contribute to the… read more here.

Keywords: hypoxia; vasa recta; dvr; kidney slices ... See more keywords
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Nitric Oxide Signalling in Descending Vasa Recta after Hypoxia/Re-Oxygenation

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23137016

Abstract: Reduced renal medullary oxygen supply is a key factor in the pathogenesis of acute kidney injury (AKI). As the medulla exclusively receives blood through descending vasa recta (DVR), dilating these microvessels after AKI may help… read more here.

Keywords: descending vasa; oxygenation; nitric oxide; hypoxia ... See more keywords