Articles with "vascular adhesion" as a keyword



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Population pharmacokinetics and pharmacodynamics of a novel vascular adhesion protein-1 inhibitor using a multiple-target mediated drug disposition model

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Published in 2020 at "Journal of Pharmacokinetics and Pharmacodynamics"

DOI: 10.1007/s10928-020-09717-w

Abstract: ASP8232 is a novel inhibitor of vascular adhesion protein-1 that was under evaluation for reducing residual albuminuria in patients with diabetic kidney disease. To characterize the pharmacokinetics (PK) of ASP8232 and its effect on vascular… read more here.

Keywords: vascular adhesion; adhesion protein; drug; target ... See more keywords