Biomarkers for vascular ageing in aorta tissues and blood samples
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2019.110741
Abstract: OBJECTIVES Functional and quantitative alterations and senescence of circulating and expanded endothelial progenitor cells (EPC), as well as systemic and tissue modifications of angiogenetic and inflammatory molecules, were evaluated for predicting age-related vessel wall remodeling,… read more here.
Keywords: mean age; old people; age; age range ... See more keywords
Developing technologies to assess vascular ageing: a roadmap from VascAgeNet
Sign Up to like & getrecommendations! Published in 2024 at "Physiological Measurement"
DOI: 10.1088/1361-6579/ad548e
Abstract: Vascular ageing (vascular ageing) is the deterioration of arterial structure and function which occurs naturally with age, and which can be accelerated with disease. Measurements of vascular ageing are emerging as markers of cardiovascular risk,… read more here.
Keywords: developing technologies; roadmap vascagenet; ageing roadmap; assess vascular ... See more keywords
Oxidative DNA damage promotes vascular ageing associated with changes in extracellular matrix-regulating proteins
Sign Up to like & getrecommendations! Published in 2024 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvae091
Abstract: Abstract Aims Vascular ageing is characterized by vessel stiffening, with increased deposition of extracellular matrix (ECM) proteins including collagens. Oxidative DNA damage occurs in vascular ageing, but how it regulates ECM proteins and vascular stiffening… read more here.
Keywords: dna damage; ageing associated; oxidative dna; vascular ageing ... See more keywords
Endothelial LRRC8A delays vascular ageing in natural and accelerated ageing mouse models.
Sign Up to like & getrecommendations! Published in 2025 at "Cardiovascular research"
DOI: 10.1093/cvr/cvaf212
Abstract: AIMS Vascular ageing (VA), characterised by vascular endothelial dysfunction, is a major contributor to age-related chronic conditions. Leucine-rich repeat-containing protein 8A (LRRC8A) is vital in maintaining vascular endothelial function; however, the role of endothelial LRRC8A… read more here.
Keywords: ageing natural; delays vascular; vascular ageing; endothelial lrrc8a ... See more keywords
Deletion of METTL14, a key methylation regulator, attenuates vascular ageing
Sign Up to like & getrecommendations! Published in 2025 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehaf476
Abstract: Abstract Background and Aims Vascular ageing often accompanies inflammation, contributing to the onset of local or systemic vascular diseases. Nevertheless, limited research focuses on pivotal factors triggering chronic vascular inflammation and associated pathological changes. This… read more here.
Keywords: mettl14 key; mettl14; aortic endothelial; deletion mettl14 ... See more keywords
Cardiovascular ageing definition: a scoping review on conceptual and operational frameworks.
Sign Up to like & getrecommendations! Published in 2025 at "European journal of preventive cardiology"
DOI: 10.1093/eurjpc/zwaf741
Abstract: Cardiovascular ageing involves changes such as arterial stiffening, myocardial remodelling, and systemic inflammation, which are linked to health decline, disease, and mortality. Despite advancements in understanding these mechanisms, establishing a concise and joined definition of… read more here.
Keywords: definition; conceptual operational; vascular ageing; scoping review ... See more keywords
EARLY VASCULAR AGEING IN PATIENTS WITH HYPOPARATHYROIDISM
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000835816.84383.c5
Abstract: Objective: Hypoparathyroidism may induce arterial damage, but underlying mechanisms are not well established. Few papers have addressed the topic, reporting an increase in central values and in carotid intima-media thickness [1][2]. The aim of this… read more here.
Keywords: vascular ageing; ageing patients; stiffness; hypoparathyroidism ... See more keywords
Parishin alleviates vascular ageing in mice by upregulation of Klotho
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17740
Abstract: Senescence of vascular endothelial cells is the major risk of vascular dysfunction and disease among elderly people. Parishin, which is a phenolic glucoside derived from Gastrodia elata, significantly prolonged yeast lifespan. However, the action of… read more here.
Keywords: vascular ageing; alleviates vascular; klotho; aged mice ... See more keywords
Consistencies and Differences in Intermediate Physiological Phenotypes of Vascular Ageing between Ischaemic Stroke Aetiologies
Sign Up to like & getrecommendations! Published in 2022 at "Cerebrovascular Diseases"
DOI: 10.1159/000525764
Abstract: Objective: Arterial stiffness, cerebral pulsatility, and beat-to-beat blood pressure variability partly mediate the relationship between hypertension and stroke, but it is unknown if these intermediate phenotypes of vascular ageing differ between stroke aetiologies. We therefore… read more here.
Keywords: vascular ageing; phenotypes vascular; stroke aetiologies; age ... See more keywords
Vascular Ageing and Aerobic Exercise
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph182010666
Abstract: Impairment of vascular function, in particular endothelial dysfunction and large elastic artery stiffening, represents a major link between ageing and cardiovascular risk. Clinical and experimental studies identified numerous mechanisms responsible for age-related decline of endothelial… read more here.
Keywords: age related; ageing aerobic; function; aerobic exercise ... See more keywords