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Published in 2025 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2025.12289
Abstract: Key Points Question What is the association between social and environmental exposures during the life course, measured by the Area Deprivation Index, and small markers of cerebrovascular disease known as vascular brain injury (VBI) found…
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Keywords:
life course;
vascular brain;
life;
brain injury ... See more keywords
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Published in 2020 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.50973
Abstract: We determined the association between ratios of plasma ceramide species of differing fatty‐acyl chain lengths and incident dementia and Alzheimer’s disease (AD) dementia in a large, community‐based sample.
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Keywords:
circulating ceramide;
risk vascular;
dementia;
ceramide ratios ... See more keywords
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Published in 2022 at "Open Heart"
DOI: 10.1136/openhrt-2022-002033
Abstract: Objective To examine sex differences in prevalence, volume and distribution of vascular brain lesions on MRI among patients with atrial fibrillation (AF). Methods In this cross-sectional analysis, we included 1743 patients with AF (27% women)…
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Keywords:
vascular brain;
sex;
atrial fibrillation;
sex differences ... See more keywords
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Published in 2022 at "Cerebrovascular diseases"
DOI: 10.1159/000527432
Abstract: BACKGROUND AND PURPOSE The circle of Willis (COW) is a circulatory anastomosis located at the base of the brain. Little is known about the association between covert vascular brain injury and COW configurations in the…
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Keywords:
cow;
brain;
brain injury;
vascular brain ... See more keywords
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Published in 2022 at "Stroke"
DOI: 10.1161/strokeaha.121.032608
Abstract: Supplemental Digital Content is available in the text. Sporadic cerebral small vessel disease (SVD) is a major contributor to vascular cognitive impairment and dementia in the aging human brain. On neuropathology, sporadic SVD is characterized…
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Keywords:
brain health;
brain;
svd;
neuropathology vascular ... See more keywords
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Published in 2022 at "Stroke"
DOI: 10.1161/strokeaha.121.032613
Abstract: Inflammation and its myriad pathways are now recognized to play both causal and consequential roles in vascular brain health. From acting as a trigger for vascular brain injury, as evidenced by the COVID-19 pandemic, to…
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Keywords:
brain health;
varying states;
vascular brain;
injury ... See more keywords
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Published in 2021 at "Neurology"
DOI: 10.1212/wnl.0000000000012765
Abstract: Background and Objectives To determine whether cognitive reserve attenuates the association of vascular brain injury with cognition. Methods Cross-sectional data were analyzed from 2 harmonized studies: the Canadian Alliance for Healthy Hearts and Healthy Minds…
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Keywords:
brain injury;
cognitive reserve;
vascular brain;
brain ... See more keywords
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Published in 2017 at "Surgical Neurology International"
DOI: 10.4103/2152-7806.200575
Abstract: Background: The occurrence of a brain tumor or intracranial vascular lesion during pregnancy is a rare event, but when it happens, it jeopardizes the lives of both the mother and infant. It also creates challenges…
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Keywords:
pregnancy;
management strategies;
neoplastic vascular;
strategies neoplastic ... See more keywords