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Published in 2022 at "Birth Defects Research"
DOI: 10.1002/bdr2.2064
Abstract: Prenatal CNS disruptions can be associated with physically separate findings. Examples include cognitive issues in septo‐optic dysplasia and sporadic and WNT1‐related unilateral cerebellar hypoplasia, and physical findings such as thinning of the corpus callosum, ventriculomegaly,…
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Keywords:
development;
brain;
disruption;
hypothesis products ... See more keywords
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Published in 2019 at "Brain Research"
DOI: 10.1016/j.brainres.2019.03.010
Abstract: Thrombin and activated protein C (APC) are known coagulation factors that exhibit profound effects in brain by acting on the protease activated receptor (PAR). The wild type (WT) proteases appear to impact cell survival powerfully,…
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Keywords:
vascular disruption;
protease;
vasculoprotection using;
apc ... See more keywords
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Published in 2017 at "Reproductive toxicology"
DOI: 10.1016/j.reprotox.2017.05.005
Abstract: Embryonic vascular disruption is an important adverse outcome pathway (AOP) as chemical disruption of cardiovascular development induces broad prenatal defects. High throughput screening (HTS) assays aid AOP development although linking in vitro data to in…
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Keywords:
vascular disruption;
disruption;
disruption adverse;
embryonic vascular ... See more keywords
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Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b05536
Abstract: Complete tumor regression is a great challenge faced by single therapy of near-infrared (NIR)-triggered hyperthermia or vascular disrupting agents. An injectable nanocomposite (NC) hydrogel is rationally designed for combined anticancer therapy based on NIR-triggered hyperthermia…
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Keywords:
therapy based;
triggered hyperthermia;
hyperthermia vascular;
vascular disruption ... See more keywords
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Published in 2017 at "International Journal of Hyperthermia"
DOI: 10.1080/02656736.2017.1308019
Abstract: Abstract The gadolinium-doped iron oxide nanoparticles (GdIONP) with greater specific power adsorption rate (SAR) than Fe3O4 was developed and its potential application in tumour therapy and particle tracking were demonstrated in transgenic adenocarcinoma of the…
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Keywords:
gadolinium doped;
vascular disruption;
hyperthermia;
iron oxide ... See more keywords