Endogenous humoral determinants of vascular endothelial dysfunction as triggers of acute poisoning complications
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4312
Abstract: The vascular endothelium is not only the semipermeable membrane that separates tissue from blood but also an organ that regulates inflammation, vascular tone, blood clotting, angiogenesis and synthesis of connective tissue proteins. It is susceptible… read more here.
Keywords: acute poisoning; dysfunction; vascular endothelium; endothelial dysfunction ... See more keywords
Erythrocyte Membrane-Coated Invisible Acoustic-Sensitive Nanoparticle for Inducing Tumor Thrombotic Infarction by Precisely Damaging Tumor Vascular Endothelium.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202201933
Abstract: Selective induction of tumor thrombus infarction is a promising antitumor strategy. Non-persistent embolism due to non-compacted thrombus and activated fibrinolytic system within the tumor large blood vessels and tumor margin recurrence are the main therapeutic… read more here.
Keywords: tumor vascular; damaging tumor; infarction; vascular endothelium ... See more keywords
Molecular imaging of the human pulmonary vascular endothelium in pulmonary hypertension: a phase II safety and proof of principle trial
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-017-3655-y
Abstract: PurposeThe adrenomedullin receptor is densely expressed in the pulmonary vascular endothelium. PulmoBind, an adrenomedullin receptor ligand, was developed for molecular diagnosis of pulmonary vascular disease. We evaluated the safety of PulmoBind SPECT imaging and its… read more here.
Keywords: vascular endothelium; phase; pulmobind; pulmonary vascular ... See more keywords
MicroRNA-520c-3p suppresses vascular endothelium dysfunction by targeting RELA and regulating the AKT and NF-κB signaling pathways
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Physiology and Biochemistry"
DOI: 10.1007/s13105-020-00779-5
Abstract: Endothelial injury, which can cause endothelial inflammation and dysfunction, is an important mechanism for the development of atherosclerotic plaque. This study aims to investigate the functional role of miR-520c-3p in vascular endothelium during inflammatory diseases… read more here.
Keywords: rela; signaling pathways; vascular endothelium; targeting rela ... See more keywords
Enhanced protection of the renal vascular endothelium improves early outcome in kidney transplantation: Preclinical investigations in pig and mouse
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-21463-1
Abstract: Ischemia reperfusion injury is one of the major complications responsible for delayed graft function in kidney transplantation. Applications to reduce reperfusion injury are essential due to the widespread use of kidneys from deceased organ donors… read more here.
Keywords: vascular endothelium; enhanced protection; kidney transplantation; protection renal ... See more keywords
The vascular endothelium plays a role in insulin action
Sign Up to like & getrecommendations! Published in 2019 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13171
Abstract: The endocrine system relies on the vasculature for delivery of hormones throughout the body, and the capillary microvasculature is the site where the hormones cross from the blood into the target tissue. Once considered an… read more here.
Keywords: vascular endothelium; insulin; endothelium; endothelium plays ... See more keywords
Nutraceuticals for prevention of atherosclerosis: Targeting monocyte infiltration to the vascular endothelium.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.13200
Abstract: Cardiovascular disease (CVD) is the leading cause of death, globally, and is a serious problem in developing countries. Preventing atherosclerosis is key to reducing the risk of developing CVD. Similar to carcinogenesis, atherogenesis can be… read more here.
Keywords: vascular endothelium; endothelium; nutraceuticals prevention; prevention atherosclerosis ... See more keywords
Active roles of dysfunctional vascular endothelium in fibrosis and cancer
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biomedical Science"
DOI: 10.1186/s12929-019-0580-3
Abstract: Chronic inflammation is the underlying pathological condition that results in fibrotic diseases. More recently, many forms of cancer have also been linked to chronic tissue inflammation. While stromal immune cells and myofibroblasts have been recognized… read more here.
Keywords: vascular endothelium; endothelium; fibrosis; inflammation ... See more keywords
Estrogen and the Vascular Endothelium: The Unanswered Questions.
Sign Up to like & getrecommendations! Published in 2023 at "Endocrinology"
DOI: 10.1210/endocr/bqad079
Abstract: Pre-menopausal women have a lower incidence of cardiovascular disease (CVD) compared to their age-matched male counterparts however this discrepancy is abolished following the transition to menopause or during low estrogen states. This, combined with a… read more here.
Keywords: estrogen; endothelium; estrogen vascular; endothelium unanswered ... See more keywords
Vascular endothelium function among male carriers of BRCA 1&2 germline mutation
Sign Up to like & getrecommendations! Published in 2019 at "Oncotarget"
DOI: 10.18632/oncotarget.27118
Abstract: Background: Breast cancer susceptibility genes 1&2 (BRCA1&2) mutations hinder DNA-repair. Germline mutations in these genes are known to cause cancer; however, they may have other consequences. In this study we evaluated for the first time,… read more here.
Keywords: vascular endothelium; mutation positive; endothelial damage; function ... See more keywords
Dietary intake of inorganic phosphorus has a stronger influence on vascular-endothelium function than organic phosphorus
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Biochemistry and Nutrition"
DOI: 10.3164/jcbn.17-97
Abstract: Phosphorus management through dietetic therapy is vital for the prevention of cardiovascular disease in chronic kidney disease patients. There are two main sources of phosphorus in the diet, organic phosphorus from protein and inorganic phosphorus… read more here.
Keywords: vascular endothelium; inorganic phosphorus; organic phosphorus; phosphorus ... See more keywords