Galectin‐3 contributes to vascular fibrosis in monocrotaline‐induced pulmonary arterial hypertension rat model
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.21879
Abstract: Galectin‐3 (Gal‐3) plays a critical role in vascular inflammation and fibrosis. The role of TGF‐β1 in mediating pulmonary vascular fibrosis is well documented; thus, we suspected that Gal‐3 could be an important factor in TGF‐β1‐induced… read more here.
Keywords: fibrosis; galectin contributes; gal; vascular fibrosis ... See more keywords
Alamandine attenuates angiotensin II-induced vascular fibrosis via inhibiting p38 MAPK pathway.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173384
Abstract: Alamandine attenuates hypertension and cardiac remodeling in spontaneously hypertensive rats (SHRs). We examined whether alamandine attenuates vascular remodeling in mice, and regulates angiotensin II (Ang II)-induced fibrosis in rat vascular smooth muscle cells (VSMCs). Alamandine… read more here.
Keywords: fibrosis; vascular fibrosis; alamandine attenuates; mice ... See more keywords
FABP3 overexpression promotes vascular fibrosis in Takayasu's arteritis via enhancing fatty acid oxidation in aorta adventitial fibroblasts.
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DOI: 10.1093/rheumatology/keab788
Abstract: OBJECTIVE To identify the role of fatty acid-binding protein-3 (FABP3) in vascular fibrosis in Takayasu's arteritis (TAK) and to explore the underlying molecular mechanism. METHODS The expression of FABP3 and extracellular matrix proteins (ECMs) were… read more here.
Keywords: fibrosis takayasu; aorta adventitial; fibrosis; fatty acid ... See more keywords
Spatial-reprogramming derived GPNMB+ macrophages interact with COL6A3+ fibroblasts to enhance vascular fibrosis in glioblastoma
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DOI: 10.1186/s13073-025-01553-2
Abstract: Neoadjuvant therapy plays an important role in the treatment of glioblastoma (GBM), but a considerable proportion of patients remain unresponsive to the combination of immune checkpoint blockade (ICB) and antiangiogenic therapy. Understanding the mechanisms underlying… read more here.
Keywords: col6a3 tafs; spatial reprogramming; glioblastoma; vascular fibrosis ... See more keywords
Autonomous Cortisol Secretion is associated with worse arterial stiffness and vascular fibrosis in primary aldosteronism - a cross-sectional study with follow-up data.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of endocrinology"
DOI: 10.1530/eje-21-1157
Abstract: OBJECTIVE The presence of autonomous cortisol secretion (ACS) in patients with primary aldosteronism (PA) is common and potentially associated with poor outcomes. The aim of this study was to investigate the association between autonomous cortisol… read more here.
Keywords: cortisol secretion; autonomous cortisol; primary aldosteronism; vascular fibrosis ... See more keywords
Ameliorative Role of DHA/EPA (Omega-3 PUFAs) in Vascular Fibrosis and Metabolic Disturbances in Rats with Metabolic Syndrome.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of oleo science"
DOI: 10.5650/jos.ess25171
Abstract: Metabolic syndrome (MetS), a leading non-communicable disease (NCD), has become a pronounced health problem. It is typified by obesity, insulin insensitivity, hypertension, and dyslipidemia, with obesity playing a central pathogenic role. Excessive adipose tissue accumulation… read more here.
Keywords: fibrosis; insulin; role; omega pufas ... See more keywords