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Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200890
Abstract: A strategy to recruit monocytes (MCs) from blood to regenerate vascular tissue from unseeded (cell‐free) tissue engineered vascular grafts is presented. When immobilized on the surface of vascular grafts, the fusion protein, H2R5 can capture… read more here.
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Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300520
Abstract: Clinically available small-diameter synthetic vascular grafts (SDVGs) have unsatisfactory patency rates due to impaired graft healing. Therefore, autologous implants are still the gold standard for small vessel replacement. Bioresorbable SDVGs may be an alternative, but… read more here.
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Published in 2022 at "Advanced science"
DOI: 10.1002/advs.202105783
Abstract: Tissue-engineered vascular grafts (TEVGs) with the ability to grow and remodel open new perspectives for cardiovascular surgery. Equipping TEVGs with synthetic polymers and biological components provides a good compromise between high structural stability and biological… read more here.
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Published in 2023 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202300073
Abstract: Endothelialization of engineered vascular grafts for replacement of small-diameter coronary arteries remains a critical challenge. The ability for an acellular vascular graft to promote endothelial cell (EC) recruitment in the body would be very beneficial.… read more here.
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Published in 2022 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-022-05123-y
Abstract: Several authors have reported the formation of slit valves as the underlying pathomechanism of space-occupying tumor bed cysts. Iatrogenic slit valves following the resection of high-grade gliomas have been linked to certain risk factors such… read more here.
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Published in 2021 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2021.02.028
Abstract: Small-caliber vascular grafts are used in a wide range of clinical conditions. However, there remains a substantial unfulfilled need for readily-available, synthetic vascular grafts with high long-term patency rate. To fulfill the translational goal for… read more here.
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Published in 2017 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2017.08.014
Abstract: There is a need for off-the-shelf, small-diameter vascular grafts that are safe and exhibit high long-term patency. Decellularized tissues can potentially be used as vascular grafts; however, thrombogenic and unpredictable remodeling properties such as intimal… read more here.
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Published in 2018 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2018.05.006
Abstract: Traditional tissue-engineered vascular grafts have yet to gain wide clinical use. The difficulty of scaling production of these cell- or biologic-based products has hindered commercialization. In situ tissue engineering bypasses such logistical challenges by using… read more here.
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Published in 2018 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2018.06.022
Abstract: Vascular grafts for free flap transfers should be of very small diameter and remain patent for approximately three weeks to supply blood until the revascularization from the surrounding tissue is established, with the autologous vein… read more here.