Tumor-Derived Pericytes Driven by EGFR Mutations Govern the Vascular and Immune Microenvironment of Gliomas
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DOI: 10.1158/0008-5472.can-20-3558
Abstract: This study identifies the EGFR-related mechanisms that govern the capacity of glioma cells to transdifferentiate into pericytes, regulating the vascular and the immune phenotype of the tumors. The extraordinary plasticity of glioma cells allows them… read more here.
Keywords: egfr mutations; tumor; gliomas; glioma cells ... See more keywords
Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury
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DOI: 10.7554/elife.43882
Abstract: Besides cardiomyocytes (CM), the heart contains numerous interstitial cell types which play key roles in heart repair, regeneration and disease, including fibroblast, vascular and immune cells. However, a comprehensive understanding of this interactive cell community… read more here.
Keywords: cell expression; vascular immune; cell; single cell ... See more keywords